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CD4+ T cells and antitumor immunity
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CD4+ T cells and antitumor immunity : ウィキペディア英語版
CD4+ T cells and antitumor immunity

Understanding of the antitumor immunity role of CD4+ T cells has grown substantially since the late 1990s. CD4+ T cells (mature T-helper cells) play an important role in modulating immune responses to pathogens and tumor cells, and are important in orchestrating overall immune responses.
== Immunosurveillance and Immunoediting ==
This discovery furthered the development of a previously hypothesized theory, the immunosurveillance theory. The immunosurveillance theory suggests that the immune system routinely patrols the cells of the body, and, upon recognition of a cell, or group of cells, that has become cancerous, it will attempt to destroy them, thus preventing the growth of some tumors. (Burnet, 1970) More recent evidence has suggested that immunosurveillance is only part of a larger role the immune system plays in fighting cancer. Remodeling of this theory has led to the progression of the immunoediting theory, in which there are 3 phases, Elimination, Equilibrium and Escape.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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